Granulomatous cheilitis contagious

Cheilitis : Overview, symptoms, causes, diagnosis

Infectious cheilitis, mostly cheilitis associated with cold sores is highly communicable. These infections are highly contagious and can be transmitted through direct or indirect contact with the victim. Some of the common transmission mediums are listed below Overview Chronic granulomatous (gran-u-LOM-uh-tus) disease (CGD) is an inherited disorder that occurs when a type of white blood cell (phagocyte) that usually helps your body fight infections doesn't work properly. As a result, the phagocytes can't protect your body from bacterial and fungal infections Cheilitis glandularis is a rare inflammatory disorder of the lip. It is mainly characterized by swelling of the lip with hyperplasia of the salivary glands; secretion of a clear, thick mucus; and variable inflammation. Enlargement and chronic exposure of the mucous membrane on the lower lip becomes affected by the environment, leading to erosion, ulceration, crusting, and, occasionally, infection Granulomatous cheilitis is a rare disorder of the lips and orofacial mucosa that was first described by Meischer 1 in 1945 as persistent or recurrent orofacial swelling secondary to lymphatic obstruction by granulomatous proliferation. It often has been described as a monosymptomatic form of Melkersson-Rosenthal syndrome (MRS)

Cheilitis, or lip inflammation, is a condition that manifests as red, dry, scaling, and itchy lips. Many different factors can cause cheilitis, such as an infection, chronic lip licking, or exposure to an allergen or irritant (including sun damage, lip cosmetics, oral hygiene products, fragrances, certain foods, as well as certain medications, such as accutane) Exfoliative cheilitis is not a contagious skin disorder. It cannot be passed on to a healthy individual nor can it be spread via air, droplets and close or direct contact with an affected individual Angular cheilitis is a condition that causes red, swollen patches in the corners of your mouth where your lips meet and make an angle. Other names for it are perleche and angular stomatitis

Chronic granulomatous disease - Symptoms and causes - Mayo

  1. What is granulomatous cheilitis? Answer: It is a rare condition where the lumpy swelling of one's lips occurs. Doctors also recognize it as cheilitis granulomatosa. Basically, it is a part of the spectrum of a disease called OFG (orofacial granulomatosis). There are various reasons for this to happen and they are an allergy and Crohn disease
  2. Granulomatous disorders - Crohn's disease - sarcoidosis - Melkersson-Rosenthal syndrome and granulomatous cheilitis - orofacial granulomatosis Swelling of the Salivary Glands 1. Inflammatory - mumps - HIV infection - HCV infection - Sjögren's syndrome - sarcoidosis 2. Obstruction - calculi - neoplasms 3. Tumours 4.
  3. Both males and females can get autosomal recessive CGD. A child needs 2 copies of a gene that doesn't work, 1 from each parent, to have autosomal recessive CGD. Any child born of carrier parents has a 25% chance of having autosomal recessive CGD, and a 50% chance of being a carrier
  4. Granulomatous rosacea is a type of rosacea, a long-term (chronic) skin condition involving inflammation of the cheeks, nose, chin, forehead, or eyelids. Rosacea causes redness and pimples, mainly across the face. Granulomatous rosacea is a type of rosacea that occurs mainly around the cheeks, eyes, and mouth
  5. Actinic cheilitis is a pre- malignant condition. It predisposes to: Intraepidermal carcinoma (Bowen disease or squamous cell carcinoma in situ) Invasive squamous cell carcinoma. Cancer of the lip is more common in smokers than in non-smokers. Other factors include oncogenic human papillomavirus ( wart virus), alcohol abuse, and immunosuppression

Angular cheilitis (AC) is a descriptive diagnosis for an inflammatory skin process of varied etiology occurring at the labial commissure - the angle of the mouth. Angular, or commissural, refers to a localized lip inflammation (i.e., cheilitis, from the Greek chilos or lips) that is distinguishable from the more generalized. Three types of localized granulomatous lesions can be distinguished: infectious granulomas, palisaded granulomas (granuloma annulare, necrobiosis lipoidica, and rheumatoid nodules), and foreign body granulomas. Disseminated granulomas can be divided into infectious, in particular tuberculosis, and noninfectious forms (autoimmune, neoplasia, etc.) Cheilitis is a broad term that describes swelling of the lip surface manifested by dry scaling and fissuring. It has four types namely atopic, granulomatous, actinic, and angular, which is the main focus of this article Granulomatous disease is an inflammatory condition of the central nervous system. Granulomatous meningoencephalomyelitis (GME) is also known under the names of inflammatory reticulosis, granulomatous reticulosis, neoplastic reticulosis and histiocytic encephalitis. Mononuclear cells accumulate in the meninges, in the brain (encephalo) and/or. Eczema on the lips, also called lip dermatitis or eczematous cheilitis, causes a characteristic redness, drying, and scaling of the lips. Eczema refers to a group of skin conditions that can cause.

Types of Cheilitis. The type of cheilitis varies as per the causes of cheilitis. The most common causes why your lips are flaky, inflamed, cracked, and blister are given below. 01. Angular Cheilitis. Angular cheilitis affects one or both corners of the mouth. Most commonly, it affects elders who suffer the loss of teeth and wear teeth Sterile nodular pyogranulomatous dermatitis in dogs usually has a spontaneous onset, with no history of trauma. Pain and pruritus are variable and, depending on the underlying trigger, systemic signs such as vomiting, abdominal pain and lethargy may be reported. Some dogs may be anorexic or have a depressed appetite Exfoliative Cheilitis is not contagious. It cannot be spread through the air or through direct contact. Therefore no preventive measures need to be used when treating a person with exfoliative cheilitis. Images. Sources. Kumar & Clark, Clinical Medicine, 5 th Ed, Chapter 22, Skin Diseases In most cases angular cheilitis isn't contagious and you can't transmit it by kissing or other physical contact. However, it is important to understand the reason why you have sores at the corner of your mouth Sarcoidosis is an idiopathic, multisystemic granulomatous disease first described by Hutchinson in 1877.11, 12 Sarcoidosis is characterized by the formation of noncaseating granulomas in virtually.

Dermatitis is a common condition that has many causes and occurs in many forms. It usually involves itchy, dry skin or a rash on swollen, reddened skin. Or it may cause the skin to blister, ooze, crust or flake off. Examples of this condition are atopic dermatitis (eczema), dandruff and contact dermatitis Fissured tongue and geographic tongue have been reported in association with chronic granulomatous disease. Melkersson-Rosenthal syndrome is a rare condition consisting of a triad of persistent or recurring lip or facial swelling, intermittent seventh (facial) nerve paralysis , and a fissured tongue. The etiology of this condition is also unknown Granulomatous Rosacea. Homeopathic Treatment for Granulomatous. Granulomatous Rosacea is a chronic inflammatory popular skin condition affecting mostly the upper part of the face, particularly developing around eyes and nose. This is an uncommon disease. Sometimes the papules can be nodular surrounded by marked erythema or redness

Cheilitis glandularis Genetic and Rare Diseases

Angular cheilitis (AC) is inflammation of one or both corners of the mouth. Often the corners are red with skin breakdown and crusting. It can also be itchy or painful. The condition can last for days to years. Angular cheilitis is a type of cheilitis (inflammation of the lips).. Angular cheilitis can be caused by infection, irritation, or allergies.. Luz Fonacier, Mark Boguniewicz, in Pediatric Allergy: Principles and Practice (Third Edition), 2016. Oral Mucous Membranes, Perioral Dermatitis and Cheilitis. Perioral dermatitis and cheilitis are common in children and are associated with lip licking, lip chewing, thumb sucking or excessive drooling. Objectively, changes may be barely visible or may vary from a mild erythema to a fiery red.

Granulomatous Cheilitis: A Stiff Upper Lip MDedge

Miescher's cheilitis, and granulomatous macrocheilitis, are synonyms of granulomatous cheilitis Angular cheilitis images, Angular cheilosis images, Angular stomatitis images, Perleche images. Authoritative facts from DermNet New Zealand DISCUSSION This is a typical clinical and historical snapshot of a very common problem: angular stomatitis. Cheilitis glandularis (7.7) Cheilitis granulomatosis of Melkersson Rosenthal syndrome and granulomatous lesions Cancrum oris (noma) occurs in severely malnourished children • Yaws, also a disease of developing countries, is a contagious, nonvenereal treponeme that mainly affects children younger than 15 years. contagious viral infection characterized by typical maculopapular or vesicular eruptions on hands, feet and in oral cavity. Since HFMD is predominantly Granulomatous cheilitis: successful treatment with clofazimine P Michalopoulos1, K Kaminska1, R Blum2, C Mainetti Less commonly, cheilitis can signal an underlying disease. Granulomatous cheilitis, a lumpy swelling of the lips, can be a symptom of Crohn's Disease, an inflammatory disease of the intestines

Cheilitis: Symptoms, Causes, Diagnosis, and Treatmen

Granulomatous cheilitis A chronic inflammatory state in the lip area may lead to granulomas. The disease usually develops in young adult patients and the clinical symptoms usually include sudden diffuse or nodular oedema of the upper lip, lower lip or the cheeks, while other areas are less frequently affected (the forehead, eyelids, hairy head. A similar condition called granulomatous cheilitis is another rare inflammatory condition that affects the upper lip, causing swollen bumps Papular cheilitis. Contagious echthyma (orf) - parapoxvirus. Goat. Papular stomatitis. intestine - granulomatous enterotyphlocolitis, Mycobacterium avium within histiocytes - ZN. Goat - serous atrophy of fat and liver atrophy - emaciation - insufficient caloric intake during winter CHEILITIS. Cheilitis is caused by different factors, which may be allergic or inflammatory. The lower lip is the most common affected. The lesion may be localized in the lip or may extend to the adjacent mucocutaneous or even to the skin of the face. Fig. 372 Cheilitis &Glossitis. Etiology of Cheilitis

Cheilitis glandularis (CG) is a clinically descriptive diagnosis that refers to an uncommon, poorly understood inflammatory disorder of the lower lip. Its etiology remains obscure. [ 1] Cheilitis glandularis is characterized by progressive enlargement and eversion of the lower labial mucosa that results in obliteration of the mucosal-vermilion. Cheilitis may also coexist with or precede the onset of numerous systemic disorders. We present a patient with an 8-year history of cheilitis. More-over, different possible underlying causes in the differential diagnosis and treatment possibilities are presented. Key words: lip diseases, vermilion, granulomatous cheilitis. Introductio Hilar Adenopathy Causes. These are the potential causes or etiologies that can lead to the appearance of the hilar adenopathy: Inflammatory. Sarcoidosis. Inorganic dust disease (silicosis, berylliosis) Malignant. Lymphoma (more often Hodgkin lymphoma, in comparison to non-Hodgkin lymphoma) Metastases. Bronchogenic carcinoma (primary hilar tumor AFIP GROSS PATHOLOGY SLIDE TEST #1 December 1993 Pathogenesis of the lesion: _Septic Emboli Occlusion of cutaneous vessels Infarcts__ 42. Tissue from a Cat (G8) Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases. When germs such as bacteria or viruses invade your body, they attack and multiply. This is called an infection. The infection causes the disease that makes you sick. Your immune system protects you from the.

Exfoliative Cheilitis - Symptoms, Causes, Contagious

The third phase of the illness is a vasculitis, which involves the skin, lungs, nerves, kidneys, and other organs. Particular mention should be made of the frequent devastating involvement of the nerves (called mononeuritis multiplex), which produces severe tingling, numbess, shooting pains, and severe muscle wasting/power loss in the hands or feet ABSTRACT The etiology of cheilitis granulomatosa is unknown. In some cases, rapid improvement and/or complete elimination of swelling of the lips after dental treatment has been reported. Here, we describe another case of improvement following dental treatment. A 57‐year‐old woman had developed asymptomatic swelling of the lower lip 2 months previously. Histological examination revealed. Granulomatous ulcer. Chronic, non-healing ulcer with yellow-gray, depressed center & irregular, well demarcated border May be caused by tuberculosis or histoplasmosis Contagious. what are the names of six infectious diseases most commonly associated with Fungal/candidiasis? Angular Cheilitis Median Rhomboid Glossitis. Well, some of the common causes of this problem include allergies, dental aesthetics and lip plastic surgeries, infected piercings on your top lip and frenulum, granulomatous cheilitis (especially if you have a lump in your swelling), cellulitis which is a bacterial infection of the skin, causes red, tender skin that is usually swollen and.

Angular cheilitis is the most common form of fungal and bacterial infection of the lips that equally affects both men and women. It is a common inflammation of the lips prevalent in adults particularly those is the 3rd to 6th decade of life while it can also affect children. It is more common in people who wear dentures or have no natural teeth. Spongiotic, Psoriasiform, and Lichenoid Dermatoses Laura E. K. Gifford Emily J. Osier Charlene W. Oldfield Judith V. Williams Alejandro A. Gru ATOPIC DERMATITIS Definition and Epidemiology Atopic dermatitis is a chronic, relapsing inflammatory skin condition defined by pruritus.1 The most widely used diagnostic criteria specify that a patient must have pruritus with an eczematous dermatiti Angular cheilitis, also known as angular stomatitis and perlèche, causes swollen, red patches in the corners on the outside of your lips. Angular cheilitis can occur on one or both sides of your. Contagious impetigo 55 Furuncle 57 Carbuncle 57 Necrotizing fasciitis 58 Chronic cheilitis 121 Granulomatous cheilitis (cheilitis granulomatosa, Miescher's cheilitis) 122 Drug-induced cheilitis (cheilitis medicamentosa) 123 Seborrheic dermatitis in the perioral region 12 Oral manifestations of systemic diseases 1. Oral Manifestations ofOral Manifestations of Systemic DiseasesSystemic Diseases Dr.Ramesh Parajuli MS(Otorhinolaryngology,Head and Neck surgery)Dr.Ramesh Parajuli MS(Otorhinolaryngology,Head and Neck surgery) Chitwan Medical College Teaching Hospital, Bharatpur-10, Chitwan, NepalChitwan Medical College Teaching Hospital, Bharatpur-10, Chitwan, Nepa

Angular cheilitis: Causes, symptoms, treatment and mor

Cheilitis is a broad term that describes inflammation of the lip surface characterized by dry scaling and fissuring. Specific types are atopic, angular, granulomatous, and actinic. Angular cheilitis is commonly seen in primary care settings, and it specifically refers to cheilitis that radiates from the commissures or corners of the mouth Stomatitis, also known as oral mucositis, is an inflammation in the mouth that affects the mucous membranes, and the condition arises from either a local stimulation or a systemic provocation. 1 The causes of stomatitis are bacterial, fungal, viral, systemic, medications, physical irritants, allergies, irradiation, and chemotherapy, leading to reactions varying from stinging, soreness, red. Herpes labialis, commonly known as cold sores, is a type of infection by the herpes simplex virus that affects primarily the lip. Symptoms typically include a burning pain followed by small blisters or sores. The first attack may also be accompanied by fever, sore throat, and enlarged lymph nodes. The rash usually heals within ten days, but the virus remains dormant in the trigeminal ganglion Feline eosinophilic granuloma complex is a term that describes a group of three different skin lesions that occur on cats. It is thought that these skin lesions are caused by a hypersensitive reaction to an irritant, such as a flea bite or an allergic reaction • Dorsum of the tongue - most commonly affected- lip, buccal mucosa, & palate • TB Esophagitis: -swallowed sputum or direct spread from adjacent lymph nodes -stricture, fistula, mucosal irregularities • Granulomatous Cheilitis- rare • Laboratory tests: Sputum culture, HPE, CXR • Treatment: ATT 32

Exfoliative cheilitis is a condition characterized by persistent scaling and flaking of the lip vermilion. The specifying exfoliative cheilitis case report states that EC is characterized by continuous desquamation of hideous, thick scales of keratin that will show lip beneath â J Med â ¦ Overgrowth of the candida yeast that is characterized by a green or yellow substance on the lips Cheilitis is a broad term that describes inflammation of the lip surface characterized by dry scaling and fissuring. Specific types are atopic, angular, granulomatous, and actinic. Angular cheilitis is commonly seen in primary care settings, and it specifically refers to cheilitis that radiates from the commissures or corners of the mout inflammation, reaction of the body to injury or to infectious, allergic, or chemical irritation. The symptoms are redness, swelling, heat, and pain resulting from dilation of the blood vessels in the affected part with loss of plasma and leucocytes (white blood cells) into the tissues. White blood cells communicate with each other via cytokines. Cheilitis is the term used to describe inflamed lips Types of cheilitis The lips can be inflamed because of an infection or skin condition: Angular cheilitis Granulomatous cheilitis Orofacial granulomatosis Crohn skin disease Actinic cheilitis Exfoliative cheilitis Glandular cheilitis Lichenoidcheilit Angular cheilitis is a highly manageable condition. Angular cheilitis is mostly curable and poses no inherent risk to life and rarely results in permanent disfigurement 12). Angular cheilitis improves within the first several days of successful treatment and typically resolves by two weeks, thus schedule a follow up then

Orofacial Granulomatosis: Some common facts and mor

Queilitis granulomatosa - Artículos - IntraMed

Sarcoidosis and Granulomatosis - Diagnosis and Management InTech Rijeka 10.5772/intechopen.92233 Chapter Granulomatous Diseases Mimicking Sarcoidosis Robles-Marhuenda Angel aroblesmarhuenda@gmail.com Unidad de Enfermedades Autoinmunes Sistémicas, Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid, Spain. Granulomatous diseases are not infrequent in daily clinical practice -contagious: easily spread within crowds more prevalent in school-aged children, but also seen in adults peak occurrence = summer/early fall initially as red macule/papule then vesicles vesicles rupture leading to thick amber crusts (cornflakes glued to surfaces) differential dx: recurrent herpes simplex, exfoliative cheilitis Thank you for your participation! * Your assessment is very important for improving the work of artificial intelligence, which forms the content of this projec

Angular cheilitis (AC) is the unwieldy medical term for inflammation at one or both corners of the mouth. AC is relatively common, and almost everyone who has it also has chapped lips. These painful sores typically begin as small cracks at the corners of the lips, which then become inflamed and red Chromoblastomycosis is a chronic, slowly progressive, non-contagious, granulomatous infection caused by several species of fungi mainly from three genera—Fonsecaea, Pialophora and Cladophialophora [45,46,47]. It has a worldwide distribution and is commonly seen in tropical and subtropical climates The disease in the lungs and skin is characterized by the formation of a granulomatous reaction with giant cells. As with other fungal diseases, there has been an increase in the recognition of pulmonary infection. The yeast may also form a mass in the mediastinum called a cryptococcoma Cracks in the lips are most commonly associated with chapped lips, medically referred to as cheilitis simplex. Cheilitis is the term that denotes inflammation of the lips. Cracking, fissuring, reddening, peeling, and pain of the lips can occur when inflammation is present. Inflammation of the lips can be caused by many different conditions; in some cases, the condition can be chronic (persists. Cheilitis is an inflammation of the lips, typically causing peeling, cracking and soreness. Angular cheilitis refers specifically to inflammation at the corners of the mouth. Many conditions and factors can precipitate transient or chronic cheilitis, including overexposure to the sun, nutritional deficiencies, allergies, medications.

Candidiasis cheilitis. Candidiasis erosion of the corners of the mouth. In the course of the process, the diagnosis of candidal stomatitis determines such forms: Acute form of candidiasis. Pseudomembranous candidiasis is a thrush. Atrophic candidiasis. Chronic candidiasis stomatitis. Hyperplastic candidiasis Impetigo is a highly contagious infection of the superficial epidermis. Histological appearance of necrotizing granulomatous inflammation with various degrees of caseation is also diagnostic. The most important differential diagnosis is TB lymphadenitis. like angular cheilitis, denture stomatitis and rhomboid median glossitis.. Arboviral meningoencephalitis (summer via tick or mosquito; West Nile virus, Eastern Equine Encephalitis virus, Western Equine Encephalitis virus, St. Louis Encephalitis virus, California group Encephalitis viruses, Powassan Encephalitis virus)- are the most common cause of episodic encephalitis in the US. Mumps (late winter and early spring It's not contagious, but anybody can get it. Women are more likely to have it than men. It's most common in people older than 40. But kids and young adults can also get it. Oral Lichen Planus Cause

Angular Cheilitis Causes and Risks. Angular Cheilitis affects people of all ages and is commonly treated in dental offices and dermatology clinics. According to theAmerican Osteopathic College of Dermatology, the cause for excess saliva around the corners of the mouth can vary and includes: Misaligned bite and orthodontic treatment Granuloma, Eosinophilic Granuloma, Parasitic Granuloma, Pyogenic Granuloma, Sperm Gun Shot Gynecomastia Habronemiasis Haemonchosis Halicephalobiasis Hamartoma Hardware Disease Heart Failure, Congestive Heart Failure, Left Side Heart Failure, Right Side Heartwater Heat Exhaustion Hemagglutinating Catarrhal Fev Hemangioma Hemangiopericytoma. Sunday, August 31, 2008. Granulomatous cheilitis is a chronic swelling of the lip due to granulomatous inflammation. Miescher cheilitis is the term used when the granulomatous changes are confined to the lip. Miescher cheilitis is generally regarded as a monosymptomatic form of the Melkersson-Rosenthal syndrome, although the possibility remains.

Granulomatous episcleritis, which is directly linked to the disease, is a sign of progression, while xerophthalmia is secondary to vitamin A Pharyngeal conjunctival fever is a highly contagious acute disease progressing in epidemic form and mainly due to type 3 adenovirus. erythematous edema of the face, cheilitis, erythema of the. What are synonyms for cheilitis Granulomatous cheilitis is the most common form of presentation of Melkersson-Rosenthal syndrome, observed in 80% of cases. 2-5 Five of our patients (83.33%) had a monosymptomatic form of Melkersson-Rosenthal syndrome (granulomatous cheilitis), whereas just 1 patient (16.66%) had an oligosymptomatic form of the.

Differential diagnosis of Oral Diseases - Dental Scienc

Melkersson-Rosenthal syndrome (cheilitis granulomatosa

Chronic Granulomatous Disease Facts, Symptoms, and Treatmen

Demodex sp. mites, Sarcocystis sp. cysts, and a granulomatous reaction to plant material were not present in all slides. Epidermal erosions were variable. Bluetongue (BT) is a noncontagious orbiviral (family Reoviridae) disease of sheep, goats, and cattle. The virus is transmitted by various species of Culicoides sp. midges (biting gnats) Common Causes of Recurrent Lip Rashes (Cheilitis) Recurrent lip rashes and rashes around the mouth can be caused by various factors such as dermatological diseases, infections, allergic reactions, chemical irritants, and physical irritants. Let's explore the most common causes of lip rashes so you can help your lips heal By. HealthPrep Staff. Angular cheilitis, also known as angular stomatitis, refers to a localized inflammation at the corners of the mouth. Either one or both corners of the mouth may be affected. Symptoms of the condition typically include crusting and cracking at the corners of the mouth, redness, skin breakdown, pain, and itching

GastroenterologyDermatology For Dentists and Dental Students: OralPath Exam 1 - Oral Maxillofacial Pathology µbiology 6252CheilitisBottom Left Lip Feels Numb | Sitelip

Having said this, a contagious oral fungal infection called Candida (also known as oral thrush) can develop inside the mouth of an angular cheilitis sufferer, characterised with a whitish coating on the tongue if the condition is not contained. Many cheilosis sufferers experience attacks a few times a year, each lasting months Central nervous system (CNS) vasculitis is inflammation of blood vessel walls in the brain or spine. (The brain and the spine make up the central nervous system.) CNS vasculitis often occurs in the following situations: Accompanied by other autoimmune diseases such as systemic lupus erythematosus, dermatomyositis and rarely, sarcoidosis and. cheilitis granulomatosa / Miescher's granulomatous cheilitis: an inflammation of the lips characterized by granulomas and swelling; it is sometimes part of Melkersson-Rosenthal syndrome; impetiginous cheilitis: impetigo of the lips. cheilitis venenata : that due to a toxic substanc Perioral dermatitis is a facial rash that is often seem among women between the ages of 16 to 45 years. Occurring around the mouth, the rash is red and slightly bumpy or scaly. The rash could be itchy and can sometimes also cause a burning sensation. A common facial problem characterized by groups of tender and itchy small red papules, perioral. Verruca vulgaris, also known as a wart, is a benign, virus-induced, focal epithelial hyperplasia. It is contagious and can spread to other parts of a person's skin or mucous membranes by way of autoinoculation. It infrequently develops on oral mucosa but is extremely common on the skin Anogenital (venereal) warts. A63.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2021 edition of ICD-10-CM A63.0 became effective on October 1, 2020. This is the American ICD-10-CM version of A63.0 - other international versions of ICD-10 A63.0 may differ